Research workbench
Crystal structure of aspartate dehydrogenase (TM1643) from thermotoga maritima at 1.9 a resolution
Analyse Crystal structure of aspartate dehydrogenase (TM1643) from thermotoga maritima… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1J5P
- Type
- protein
- Length
- 235 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aspartate dehydrogenase
- EC
- 1.4.3.16
- UniProt
- Q9X1X6
- Ligands
- NAD
- Pockets
- 3 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aspartate dehydrogenase (EC 1.4.3.16) | protein | 235 | 37% helix, 26% strand | Q9X1X6 |
Ligands and binding sites
- NAD · Nicotinamide-adenine-dinucleotide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 230 | 0.53 | 0.77 | 38 | NAD |
| 2 | 148 | 0.40 | 0.73 | 24 | empty |
| 3 | 59 | 0.37 | 0.79 | 13 | empty |
Compared structures
- 1J5P · Crystal structure of aspartate dehydrogenase (TM1643) from Thermotoga maritima at 1.9 A… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9X1X6 · AlphaFold monomer V2.0 prediction for L-aspartate dehydrogenase (Q9X1X6) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X1X6
- Elsewhere: RCSB PDB 1J5P · PDBe 1J5P · UniProt Q9X1X6
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