Research workbench
Colias eurytheme phosphoglucose isomerase. homodimer from 4-5(18) genotype.
Analyse Colias eurytheme phosphoglucose isomerase. homodimer from 4-5(18) genotype. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4WMJ
- Type
- protein
- Length
- 2,215 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glucose-6-phosphate isomerase
- EC
- 5.3.1.9
- UniProt
- G9BZJ0
- Pockets
- 16 · best druggability 0.81
Structure
x-ray diffraction · 3 distinct chains · 55% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D | Glucose-6-phosphate isomerase (EC 5.3.1.9) | protein | 553 | 56% helix, 12% strand | G9BZJ0 |
| B | Glucose-6-phosphate isomerase (EC 5.3.1.9) | protein | 555 | 54% helix, 12% strand | G9BZJ0 |
| C | Glucose-6-phosphate isomerase (EC 5.3.1.9) | protein | 554 | 54% helix, 12% strand | G9BZJ0 |
Pockets
16 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1109 | 0.81 | 0.82 | 74 | empty |
| 2 | 1109 | 0.79 | 0.80 | 73 | empty |
| 3 | 472 | 0.73 | 0.82 | 52 | empty |
| 4 | 466 | 0.71 | 0.82 | 50 | empty |
| 5 | 452 | 0.70 | 0.81 | 47 | empty |
Interfaces
5 interfaces between chains.
- A–B · 6423 Ų buried · 73 hydrogen bonds · protein-protein
- C–D · 6399 Ų buried · 73 hydrogen bonds · protein-protein
- B–D · 494 Ų buried · 2 hydrogen bonds · protein-protein
- B–C · 51 Ų buried · 0 hydrogen bonds · protein-protein
- A–D · 49 Ų buried · 0 hydrogen bonds · protein-protein
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G9BZJ0
- Elsewhere: RCSB PDB 4WMJ · PDBe 4WMJ · UniProt G9BZJ0
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