Research workbench
Crystal structure of staphylococcus capitis divalent metal ion transporter (dmt) in complex with nanobody
Analyse Crystal structure of staphylococcus capitis divalent metal ion transporter… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4WGV
- Type
- protein
- Length
- 1,030 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Divalent metal cation transporter mnth; Camelid antibody fragment, nanobody
- UniProt
- F9L8R0
- Pockets
- 20 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 56% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Divalent metal cation transporter mnth | protein | 395 | 72% helix, 0% strand | F9L8R0 |
| B, D | Camelid antibody fragment, nanobody | protein | 120 | 3% helix, 57% strand | — |
Pockets
20 pockets found on a 1 Å grid, 10 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 746 | 0.70 | 0.77 | 78 | empty |
| 2 | 67 | 0.68 | 0.95 | 26 | empty |
| 3 | 514 | 0.65 | 0.76 | 49 | empty |
| 4 | 136 | 0.64 | 0.86 | 22 | empty |
| 5 | 337 | 0.61 | 0.78 | 41 | empty |
Interfaces
4 interfaces between chains.
- D–C · 842 Ų buried · 20 hydrogen bonds · protein-protein
- A–B · 828 Ų buried · 18 hydrogen bonds · protein-protein
- A–C · 610 Ų buried · 0 hydrogen bonds · protein-protein
- B–D · 503 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F9L8R0
- Elsewhere: RCSB PDB 4WGV · PDBe 4WGV · UniProt F9L8R0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.