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Structure of artocarpin: a lectin with mannose specificity (form 1)

Analyse Structure of artocarpin: a lectin with mannose specificity (form 1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1J4S
Type: protein
Length: 596 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Artocarpin
UniProt: Q7M1T4
Pockets: 3 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 56% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	Artocarpin	protein	149	0% helix, 56% strand	Q7M1T4

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	473	0.80	0.88	71	empty
2	58	0.44	0.83	22	empty
3	66	0.33	0.76	18	empty

Interfaces

6 interfaces between chains.

C–D · 965 Å² buried · 17 hydrogen bonds · protein-protein
A–B · 943 Å² buried · 16 hydrogen bonds · protein-protein
A–C · 627 Å² buried · 10 hydrogen bonds · protein-protein
B–D · 619 Å² buried · 10 hydrogen bonds · protein-protein
B–C · 63 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

1J4S · Structure of Artocarpin: a Lectin with Mannose Specificity (Form 1) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7M1T4
Elsewhere: RCSB PDB 1J4S · PDBe 1J4S · UniProt Q7M1T4

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