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Crystal structure of an aromatic amino acid aminotransferase from burkholderia cenocepacia J2315

Analyse Crystal structure of an aromatic amino acid aminotransferase from burkholderia… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4WD2
Type: protein
Length: 398 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Aromatic-amino-acid transaminase tyrb
EC: 2.6.1.57
UniProt: T0EWC0
Pockets: 3 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Aromatic-amino-acid transaminase tyrb (EC 2.6.1.57)	protein	398	46% helix, 13% strand	T0EWC0

Ligands and binding sites

GOL · Glycerol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	105	0.41	0.76	24	empty
2	87	0.32	0.73	16	empty
3	73	0.31	0.74	17	GOL

Modifications

Observed in the structure: 1 modified (cofactor).

Compared structures

4WD2 · Crystal structure of an aromatic amino acid aminotransferase from Burkholderia… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt T0EWC0
Elsewhere: RCSB PDB 4WD2 · PDBe 4WD2 · UniProt T0EWC0

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