Research workbench
Structure of tRNA-processing enzyme complex 4
Analyse Structure of tRNA-processing enzyme complex 4 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4WC6
- Type
- protein + RNA
- Length
- 442 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Poly a polymerase; RNA (75-mer)
- UniProt
- O66728
- Ligands
- ATP
- Pockets
- 9 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 57% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Poly a polymerase | protein | 367 | 57% helix, 11% strand | O66728 |
| B | RNA (75-mer) | rna | 75 | — | — |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 986 | 0.75 | 0.78 | 64 | ATP |
| 2 | 932 | 0.71 | 0.77 | 43 | empty |
| 3 | 492 | 0.69 | 0.80 | 41 | empty |
| 4 | 387 | 0.58 | 0.76 | 24 | empty |
| 5 | 121 | 0.44 | 0.77 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 1059 Ų buried · 7 hydrogen bonds · protein-nucleic
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O66728
- Elsewhere: RCSB PDB 4WC6 · PDBe 4WC6 · UniProt O66728
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.