Research workbench
Q/E mutant SA11 NSP4_CCD
Analyse Q/E mutant SA11 NSP4_CCD in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4WBA
- Type
- protein
- Length
- 207 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Non-structural glycoprotein NSP4
- UniProt
- O92323
- Ligands
- PO4
- Pockets
- 2 · best druggability 0.86
Structure
x-ray diffraction · 2 distinct chains · 94% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, E | Non-structural glycoprotein NSP4 | protein | 42 | 95% helix, 0% strand | O92323 |
| B, C, D | Non-structural glycoprotein NSP4 | protein | 41 | 93% helix, 0% strand | O92323 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains A, B, C, D, E
- GOL · Glycerol · additive · 2 copies · chains A, B, C, D, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 356 | 0.86 | 0.94 | 40 | GOL |
| 2 | 285 | 0.77 | 0.88 | 41 | PO4 |
Interfaces
10 interfaces between chains.
- D–E · 1107 Ų buried · 6 hydrogen bonds · protein-protein
- A–C · 1087 Ų buried · 7 hydrogen bonds · protein-protein
- B–E · 1075 Ų buried · 5 hydrogen bonds · protein-protein
- A–D · 1028 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 997 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 4WBA · Q/E mutant SA11 NSP4_CCD · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O92323
- Elsewhere: RCSB PDB 4WBA · PDBe 4WBA · UniProt O92323
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.