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The crystal structure of human ABL1 wild type kinase domain in complex with axitinib

Analyse The crystal structure of human ABL1 wild type kinase domain in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4WA9
Type
protein
Length
522 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P00519

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
B—protein276—P00519
A—protein246—P00519

Compared structures

  • 4WA9 · The crystal structure of human abl1 wild type kinase domain in complex with axitinib · the same entry in another collection · chain B against B, TM-score 1.00
  • P00519 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase ABL1 (P00519) · a predicted model of the same protein · chain B against A, TM-score 0.94

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