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Crystal structure of full-length split GFP mutant D117C disulfide dimer, P 64 2 2 space group

Analyse Crystal structure of full-length split GFP mutant D117C disulfide dimer, P 64 2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4W6O
Type: protein
Length: 204 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fluorescent protein D117C
Ligands: CRO
Pockets: 4 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fluorescent protein D117C	protein	204	5% helix, 50% strand	—

Ligands and binding sites

CRO · {2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	117	0.79	0.97	31	CRO
2	77	0.40	0.79	21	empty
3	55	0.37	0.80	13	empty
4	54	0.36	0.79	12	empty

Modifications

Observed in the structure: 2 cofactor (chromophore).

Compared structures

4W6O · Crystal Structure of Full-Length Split GFP Mutant D117C Disulfide Dimer, P 64 2 2 Space… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4W6O · PDBe 4W6O

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