Research workbench
Crystal structure of ESPG3 from the esx-3 type VII secretion system of M. tuberculosis
Analyse Crystal structure of ESPG3 from the esx-3 type VII secretion system of M.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4W4I
- Type
- protein
- Length
- 269 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Esx-3 secretion-associated protein ESPG3
- UniProt
- P9WJC6
- Ligands
- SO4
- Pockets
- 5 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Esx-3 secretion-associated protein ESPG3 | protein | 269 | 33% helix, 29% strand | P9WJC6 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 258 | 0.64 | 0.82 | 26 | empty |
| 2 | 166 | 0.50 | 0.78 | 29 | empty |
| 3 | 57 | 0.34 | 0.77 | 19 | empty |
| 4 | 69 | 0.32 | 0.75 | 17 | empty |
| 5 | 50 | 0.25 | 0.73 | 17 | empty |
Compared structures
- 4W4I · Crystal structure of EspG3 from the ESX-3 type VII secretion system of M. tuberculosis · the same entry in another collection · chain A against A, TM-score 1.00
- P9WJC6 · AlphaFold monomer V2.0 prediction for esx-3 secretion-associated protein ESPG3 (P9WJC6) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WJC6
- Elsewhere: RCSB PDB 4W4I · PDBe 4W4I · UniProt P9WJC6
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