Research workbench
Crystal structure of RV3557C/KSTR2, a transcriptional repressor involved in cholesterol metabolism in mycobacterium tuberculosis
Analyse Crystal structure of RV3557C/KSTR2, a transcriptional repressor involved in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4W1U
- Type
- protein
- Length
- 193 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hth-type transcriptional repressor KSTR2
- UniProt
- P9WMB9
- Pockets
- 2 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hth-type transcriptional repressor KSTR2 | protein | 193 | 73% helix, 0% strand | P9WMB9 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 180 | 0.60 | 0.82 | 24 | empty |
| 2 | 83 | 0.41 | 0.78 | 14 | empty |
Compared structures
- 4W1U · Crystal structure of Rv3557c/KstR2, a transcriptional repressor involved in cholesterol… · the same entry in another collection · chain A against A, TM-score 1.00
- P9WMB9 · AlphaFold monomer V2.0 prediction for hth-type transcriptional repressor KSTR2 (P9WMB9) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WMB9
- Elsewhere: RCSB PDB 4W1U · PDBe 4W1U · UniProt P9WMB9
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