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In meso crystal structure of the pot family transporter peptso

Analyse In meso crystal structure of the pot family transporter peptso in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4UVM
Type: protein
Length: 505 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutathione uptake transporter
UniProt: Q8EKT7
Ligands: 78N, 78M
Pockets: 5 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 79% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutathione uptake transporter	protein	505	79% helix, 0% strand	Q8EKT7

Ligands and binding sites

78N · (2R)-2,3-dihydroxypropyl(7z)-pentadec-7-enoate · ligand · 4 copies · chains A
78M · (2S)-2,3-dihydroxypropyl(7z)-pentadec-7-enoate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1009	0.82	0.83	102	78N
2	171	0.56	0.80	22	78N
3	244	0.52	0.75	28	78M
4	196	0.52	0.77	27	empty
5	78	0.41	0.79	21	empty

Compared structures

4UVM · In meso crystal structure of the POT family transporter PepTSo · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8EKT7
Elsewhere: RCSB PDB 4UVM · PDBe 4UVM · UniProt Q8EKT7

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