Research workbench
The structure of the immature HIV-1 capsid in intact virus particles at sub-nm resolution
Analyse The structure of the immature HIV-1 capsid in intact virus particles at sub-nm… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4USN
- Type
- protein
- Length
- 3,780 residues
- Chains
- 18
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- P24
- UniProt
- Q9IVM8
- Pockets
- 20 · best druggability 0.46
Structure
electron microscopy · 1 distinct chain · 64% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R | P24 | protein | 210 | 64% helix, 0% strand | Q9IVM8 |
Pockets
20 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 236 | 0.46 | 0.74 | 55 | empty |
| 2 | 261 | 0.45 | 0.73 | 55 | empty |
| 3 | 238 | 0.43 | 0.72 | 48 | empty |
| 4 | 217 | 0.42 | 0.72 | 49 | empty |
| 5 | 199 | 0.40 | 0.72 | 49 | empty |
Interfaces
26 interfaces between chains.
- E–F · 125 Ų buried · 0 hydrogen bonds · protein-protein
- K–L · 101 Ų buried · 1 hydrogen bond · protein-protein
- D–E · 93 Ų buried · 1 hydrogen bond · protein-protein
- A–F · 92 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 88 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4USN · The structure of the immature HIV-1 capsid in intact virus particles at sub-nm resolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9IVM8
- Elsewhere: RCSB PDB 4USN · PDBe 4USN · UniProt Q9IVM8
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