Research workbench
Wcbl complex with glycerol bound to sugar site
Analyse Wcbl complex with glycerol bound to sugar site in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4USM
- Type
- protein
- Length
- 690 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative sugar kinase
- EC
- 2.7.1.167
- UniProt
- H7C745
- Ligands
- CL
- Pockets
- 4 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Putative sugar kinase (EC 2.7.1.167) | protein | 345 | 43% helix, 25% strand | H7C745 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 765 | 0.74 | 0.79 | 70 | empty |
| 2 | 359 | 0.67 | 0.81 | 51 | GOL, CL |
| 3 | 397 | 0.66 | 0.80 | 58 | GOL, CL |
| 4 | 282 | 0.51 | 0.74 | 46 | empty |
Interfaces
1 interface between chains.
- A–B · 977 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 4USM · WcbL complex with glycerol bound to sugar site · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt H7C745
- Elsewhere: RCSB PDB 4USM · PDBe 4USM · UniProt H7C745
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