Research workbench
Crystal structure of entamoeba histolytica lysyl-tRNA synthetase apo form
Analyse Crystal structure of entamoeba histolytica lysyl-tRNA synthetase apo form in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4UP8
- Type
- protein
- Length
- 580 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lysine--tRNA ligase
- EC
- 6.1.1.6
- UniProt
- C4M7X2
- Pockets
- 6 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lysine--tRNA ligase (EC 6.1.1.6) | protein | 580 | 39% helix, 22% strand | C4M7X2 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 859 | 0.75 | 0.79 | 74 | empty |
| 2 | 269 | 0.64 | 0.81 | 39 | empty |
| 3 | 304 | 0.55 | 0.76 | 41 | empty |
| 4 | 357 | 0.54 | 0.74 | 46 | empty |
| 5 | 65 | 0.34 | 0.76 | 14 | empty |
Compared structures
- 4UP8 · Crystal structure of Entamoeba histolytica lysyl-tRNA synthetase apo form · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C4M7X2
- Elsewhere: RCSB PDB 4UP8 · PDBe 4UP8 · UniProt C4M7X2
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