Research workbench
Laboratory evolved variant R-C1B1D33 of potato epoxide hydrolase STEH1
Analyse Laboratory evolved variant R-C1B1D33 of potato epoxide hydrolase STEH1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4UFP
- Type
- protein
- Length
- 638 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Epoxide hydrolase
- EC
- 3.3.2.3
- UniProt
- Q41415
- Pockets
- 4 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Epoxide hydrolase (EC 3.3.2.3) | protein | 319 | 43% helix, 17% strand | Q41415 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 468 | 0.81 | 0.87 | 59 | empty |
| 2 | 593 | 0.80 | 0.85 | 66 | empty |
| 3 | 381 | 0.63 | 0.78 | 50 | empty |
| 4 | 52 | 0.28 | 0.75 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 590 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 4UFP · Laboratory evolved variant R-C1B1D33 of potato epoxide hydrolase StEH1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q41415
- Elsewhere: RCSB PDB 4UFP · PDBe 4UFP · UniProt Q41415
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