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N-terminal globular domain of the rsv nucleoprotein

Analyse N-terminal globular domain of the rsv nucleoprotein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4UC7
Type: protein
Length: 431 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nucleoprotein
UniProt: P03418
Ligands: SO4
Pockets: 7 · best druggability 0.65

Structure

x-ray diffraction · 2 distinct chains · 62% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nucleoprotein	protein	215	64% helix, 10% strand	P03418
B	Nucleoprotein	protein	216	61% helix, 7% strand	P03418

Ligands and binding sites

SO4 · Sulfate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	550	0.65	0.76	58	empty
2	105	0.41	0.76	23	empty
3	62	0.39	0.79	13	empty
4	70	0.35	0.77	13	empty
5	55	0.32	0.77	15	empty

Interfaces

1 interface between chains.

A–B · 400 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

4UC7 · N-terminal globular domain of the RSV Nucleoprotein · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03418
Elsewhere: RCSB PDB 4UC7 · PDBe 4UC7 · UniProt P03418

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