Research workbench

X-ray structure of mg-bound human sorcin

Analyse X-ray structure of mg-bound human sorcin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4U8D
Type: protein
Length: 344 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sorcin
UniProt: P30626
Ligands: MG
Pockets: 3 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 58% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Sorcin	protein	172	58% helix, 8% strand	P30626

Ligands and binding sites

MG · Magnesium ion · metal · 7 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	219	0.61	0.81	36	empty
2	371	0.60	0.77	50	empty
3	65	0.28	0.73	15	empty

Interfaces

1 interface between chains.

A–B · 1865 Å² buried · 27 hydrogen bonds · protein-protein

Compared structures

4U8D · X-ray structure of Mg-bound human sorcin · the same entry in another collection · chain A against A, TM-score 1.00
P30626 · AlphaFold monomer V2.0 prediction for sorcin (P30626) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P30626
Elsewhere: RCSB PDB 4U8D · PDBe 4U8D · UniProt P30626

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.