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Crystal structure of recombinant TP0435 from treponema pallidum

Analyse Crystal structure of recombinant TP0435 from treponema pallidum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4U3Q
Type: protein
Length: 192 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 17 kda lipoprotein
UniProt: P29722
Pockets: 1 · best druggability 0.38

Structure

x-ray diffraction · 2 distinct chains · 15% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	17 kda lipoprotein	protein	93	15% helix, 54% strand	P29722
B	17 kda lipoprotein	protein	99	14% helix, 55% strand	P29722

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	129	0.38	0.73	24	empty

Interfaces

1 interface between chains.

A–B · 167 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4U3Q · Crystal Structure of Recombinant TP0435 from Treponema pallidum · the same entry in another collection · chain A against A, TM-score 1.00
P29722 · AlphaFold monomer V2.0 prediction for 17 kda lipoprotein (P29722) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29722
Elsewhere: RCSB PDB 4U3Q · PDBe 4U3Q · UniProt P29722

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