Research workbench
Crystal structure of cbnr, a lysr family transcriptional regulator
Analyse Crystal structure of cbnr, a lysr family transcriptional regulator in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1IZ1
- Type
- protein
- Length
- 1,170 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lysr-type regulatory protein
- UniProt
- Q9WXC7
- Pockets
- 13 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 47% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, P, Q | Lysr-type regulatory protein | protein | 292 | 46% helix, 25% strand | Q9WXC7 |
| B | Lysr-type regulatory protein | protein | 294 | 48% helix, 24% strand | Q9WXC7 |
Pockets
13 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 966 | 0.77 | 0.79 | 123 | empty |
| 2 | 509 | 0.72 | 0.81 | 75 | empty |
| 3 | 129 | 0.57 | 0.84 | 24 | empty |
| 4 | 168 | 0.44 | 0.75 | 30 | empty |
| 5 | 166 | 0.41 | 0.73 | 24 | empty |
Interfaces
5 interfaces between chains.
- B–P · 1364 Ų buried · 11 hydrogen bonds · protein-protein
- A–Q · 1310 Ų buried · 7 hydrogen bonds · protein-protein
- P–Q · 1288 Ų buried · 13 hydrogen bonds · protein-protein
- A–B · 1221 Ų buried · 8 hydrogen bonds · protein-protein
- A–P · 862 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 1IZ1 · Crystal structure of cbnr, a lysr family transcriptional regulator · the same entry in another collection · chain P against P, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WXC7
- Elsewhere: RCSB PDB 1IZ1 · PDBe 1IZ1 · UniProt Q9WXC7
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