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Crystal structure of DNA polymerase sliding clamp from pseudomonas aeruginosa

Analyse Crystal structure of DNA polymerase sliding clamp from pseudomonas aeruginosa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4TR8
Type: protein
Length: 740 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA polymerase III subunit beta
EC: 2.7.7.7
UniProt: V4MZL6
Ligands: NA
Pockets: 3 · best druggability 0.38

Structure

x-ray diffraction · 2 distinct chains · 22% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA polymerase III subunit beta (EC 2.7.7.7)	protein	379	21% helix, 42% strand	V4MZL6
B	DNA polymerase III subunit beta (EC 2.7.7.7)	protein	361	22% helix, 43% strand	V4MZL6

Ligands and binding sites

NA · Sodium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.38	0.80	16	empty
2	70	0.35	0.76	17	empty
3	55	0.30	0.76	15	empty

Interfaces

1 interface between chains.

A–B · 1231 Å² buried · 25 hydrogen bonds · protein-protein

Compared structures

4TR8 · Crystal structure of DNA polymerase sliding clamp from Pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt V4MZL6
Elsewhere: RCSB PDB 4TR8 · PDBe 4TR8 · UniProt V4MZL6

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