Research workbench
Crystal structure of human ATG5-tecair
Analyse Crystal structure of human ATG5-tecair in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4TQ1
- Type
- protein
- Length
- 290 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Autophagy protein 5; Tectonin beta-propeller repeat-containing protein 1
- UniProt
- Q9H1Y0, Q7Z6L1
- Pockets
- 1 · best druggability 0.30
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Autophagy protein 5 | protein | 258 | 37% helix, 19% strand | Q9H1Y0 |
| B | Tectonin beta-propeller repeat-containing protein 1 | protein | 32 | 56% helix, 6% strand | Q7Z6L1 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.30 | 0.75 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1303 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 4TQ1 · Crystal structure of human ATG5-TECAIR · the same entry in another collection · chain A against A, TM-score 1.00
- Q9H1Y0 · AlphaFold monomer V2.0 prediction for autophagy protein 5 (Q9H1Y0) · a predicted model of the same protein · chain A against A, TM-score 0.96
- Q7Z6L1 · AlphaFold monomer V2.0 prediction for tectonin beta-propeller repeat- containing protein… · a predicted model of the same protein · chain B against A, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H1Y0
- Every structure of UniProt Q7Z6L1
- Elsewhere: RCSB PDB 4TQ1 · PDBe 4TQ1 · UniProt Q9H1Y0 · UniProt Q7Z6L1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.