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Crystal structure of plasmodium falciparum putative histone methyltransferase PFL0690C

Analyse Crystal structure of plasmodium falciparum putative histone methyltransferase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4RZ0
Type: protein
Length: 224 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PFL0690C
UniProt: W7FLI1
Ligands: UNX
Pockets: 3 · best druggability 0.55

Structure

x-ray diffraction · 2 distinct chains · 8% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PFL0690C	protein	114	8% helix, 44% strand	W7FLI1
B	PFL0690C	protein	110	8% helix, 47% strand	W7FLI1

Ligands and binding sites

UNX · Unknown atom or ion · ion · 7 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	227	0.55	0.78	30	UNX
2	91	0.36	0.75	21	UNX
3	55	0.28	0.74	14	empty

Interfaces

1 interface between chains.

A–B · 927 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

4RZ0 · Crystal Structure of Plasmodium falciparum putative histone methyltransferase PFL0690c · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt W7FLI1
Elsewhere: RCSB PDB 4RZ0 · PDBe 4RZ0 · UniProt W7FLI1

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