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Crystal structure of apo dimer of bctspo

Analyse Crystal structure of apo dimer of bctspo in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4RYJ
Type: protein
Length: 302 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Integral membrane protein
UniProt: Q81BL7
Pockets: 3 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Integral membrane protein	protein	151	80% helix, 0% strand	Q81BL7

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	889	0.85	0.86	94	empty
2	411	0.63	0.77	34	empty
3	71	0.33	0.74	11	empty

Interfaces

1 interface between chains.

A–B · 497 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

4RYJ · Crystal structure of apo dimer of BcTSPO · the same entry in another collection · chain A against A, TM-score 1.00
Q81BL7 · AlphaFold monomer V2.0 prediction for tryptophan-rich protein tspo (Q81BL7) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q81BL7
Elsewhere: RCSB PDB 4RYJ · PDBe 4RYJ · UniProt Q81BL7

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