Research workbench
Crystal structure of the E. COLI MANGANASE(III) superoxide dismutase mutant Y174F at 0.90 ångströms resolution.
Analyse Crystal structure of the E. COLI MANGANASE(III) superoxide dismutase mutant… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1IX9
- Type
- protein
- Length
- 410 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Superoxide dismutase
- EC
- 1.15.1.1
- UniProt
- P00448
- Ligands
- MN
- Pockets
- 2 · best druggability 0.48
Structure
x-ray diffraction · 1 distinct chain · 57% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Superoxide dismutase (EC 1.15.1.1) | protein | 205 | 57% helix, 12% strand | P00448 |
Ligands and binding sites
- MN · Manganese (II) ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 120 | 0.48 | 0.79 | 23 | empty |
| 2 | 138 | 0.46 | 0.77 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 982 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 1IX9 · Crystal Structure of the E. coli Manganase(III) superoxide dismutase mutant Y174F at 0.90… · the same entry in another collection · chain A against A, TM-score 1.00
- P00448 · AlphaFold monomer V2.0 prediction for superoxide dismutase [mn] (P00448) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00448
- Elsewhere: RCSB PDB 1IX9 · PDBe 1IX9 · UniProt P00448
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.