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Crystal structure of human glutaredoxin with mesna

Analyse Crystal structure of human glutaredoxin with mesna in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4RQR
Type: protein
Length: 107 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutaredoxin-1
UniProt: P35754
Ligands: COM

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutaredoxin-1	protein	107	47% helix, 19% strand	P35754

Ligands and binding sites

COM · 1-thioethanesulfonic acid · ligand · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 2 covalent, 1 disulfide (covalent ligand, disulfide).

Compared structures

4RQR · Crystal Structure of Human Glutaredoxin with MESNA · the same entry in another collection · chain A against A, TM-score 1.00
P35754 · AlphaFold monomer V2.0 prediction for glutaredoxin-1 (P35754) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35754
Elsewhere: RCSB PDB 4RQR · PDBe 4RQR · UniProt P35754

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