Research workbench

Crystal structure of the sat domain from the non-reducing fungal polyketide synthase cazm

Analyse Crystal structure of the sat domain from the non-reducing fungal polyketide… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4RO5
Type: protein
Length: 390 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sat domain from cazm
UniProt: Q2GWK9
Pockets: 4 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sat domain from cazm	protein	390	52% helix, 13% strand	Q2GWK9

Ligands and binding sites

GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	335	0.71	0.83	63	GOL
2	80	0.43	0.80	13	empty
3	62	0.39	0.79	16	empty
4	67	0.37	0.77	13	empty

Modifications

Observed in the structure: 7 modified (engineered).

Compared structures

4RO5 · Crystal structure of the SAT domain from the non-reducing fungal polyketide synthase CazM · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2GWK9
Elsewhere: RCSB PDB 4RO5 · PDBe 4RO5 · UniProt Q2GWK9

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.