Research workbench
Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6
Analyse Psychrophilic aromatic amino acids aminotransferase from psychrobacter sp. B6 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4RKC
- Type
- protein
- Length
- 796 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aromatic amino acid aminotransferase
- EC
- 2.6.1.57
- UniProt
- C7E5X4
- Ligands
- PMP, MG, NO3
- Pockets
- 7 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Aromatic amino acid aminotransferase (EC 2.6.1.57) | protein | 398 | 47% helix, 12% strand | C7E5X4 |
Ligands and binding sites
- PMP · 4'-deoxy-4'-aminopyridoxal-5'-phosphate · ligand · 2 copies · chains A, B
- MG · Magnesium ion · metal · 2 copies · chains A, B
- NO3 · Nitrate ion · ion · 10 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 463 | 0.72 | 0.82 | 67 | NO3, PMP |
| 2 | 309 | 0.70 | 0.84 | 51 | NO3, PMP |
| 3 | 87 | 0.45 | 0.81 | 22 | MG |
| 4 | 53 | 0.38 | 0.81 | 17 | empty |
| 5 | 102 | 0.38 | 0.75 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 3278 Ų buried · 48 hydrogen bonds · protein-protein
Compared structures
- 4RKC · Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C7E5X4
- Elsewhere: RCSB PDB 4RKC · PDBe 4RKC · UniProt C7E5X4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.