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Landomycin glycosyltransferase LANGT2

Analyse Landomycin glycosyltransferase LANGT2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4RIE
Type
protein
Length
709 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Glycosyl transferase homolog
UniProt
Q9ZGC0
Pockets
7 · best druggability 0.78

Structure

x-ray diffraction · 2 distinct chains · 47% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGlycosyl transferase homologprotein35847% helix, 16% strandQ9ZGC0
BGlycosyl transferase homologprotein35147% helix, 17% strandQ9ZGC0

Pockets

7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19460.780.8074empty
25040.690.7970empty
33500.600.7732empty
41370.570.8327empty
51350.530.8126empty

Interfaces

1 interface between chains.

  • A–B · 1553 Ų buried · 20 hydrogen bonds · protein-protein

Compared structures

  • 4RIE · Landomycin Glycosyltransferase LanGT2 · the same entry in another collection · chain A against A, TM-score 1.00

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