Research workbench
Spore photoproduct lyase C140A/S76C mutant with bound adomet
Analyse Spore photoproduct lyase C140A/S76C mutant with bound adomet in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4RH0
- Type
- protein
- Length
- 340 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Spore photoproduct lyase
- EC
- 4.1.99.14
- UniProt
- A4IQU1
- Ligands
- EEM, SF4, SO4
- Pockets
- 3 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Spore photoproduct lyase (EC 4.1.99.14) | protein | 340 | 38% helix, 22% strand | A4IQU1 |
Ligands and binding sites
- EEM · [(3S)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium · ligand · chains A
- SF4 · Iron/sulfur cluster · ligand · chains A
- SO4 · Sulfate ion · ion · 6 copies · chains A
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 939 | 0.79 | 0.81 | 91 | EEM, SO4, EDO, SF4 |
| 2 | 51 | 0.31 | 0.77 | 11 | empty |
| 3 | 50 | 0.28 | 0.74 | 10 | empty |
Compared structures
- 4RH0 · Spore photoproduct lyase C140A/S76C mutant with bound AdoMet · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4IQU1
- Elsewhere: RCSB PDB 4RH0 · PDBe 4RH0 · UniProt A4IQU1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.