Research workbench
Crystal structure of the GRASP65-GM130 C-terminal peptide complex
Analyse Crystal structure of the GRASP65-GM130 C-terminal peptide complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4REY
- Type
- protein
- Length
- 218 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Golgi reassembly-stacking protein 1; Golgin subfamily a member 2
- UniProt
- Q9BQQ3, Q08379
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.38
Structure
x-ray diffraction · 2 distinct chains · 12% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Golgi reassembly-stacking protein 1 | protein | 196 | 14% helix, 34% strand | Q9BQQ3 |
| B | Golgin subfamily a member 2 | protein | 22 | 0% helix, 18% strand | Q08379 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.38 | 0.79 | 19 | empty |
| 2 | 78 | 0.31 | 0.73 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1246 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 4REY · Crystal Structure of the GRASP65-GM130 C-terminal peptide complex · the same entry in another collection · chain A against A, TM-score 1.00
- Q9BQQ3 · AlphaFold monomer V2.0 prediction for golgi reassembly-stacking protein 1 (Q9BQQ3) · a predicted model of the same protein · chain A against A, TM-score 0.79
- Q08379 · AlphaFold monomer V2.0 prediction for golgin subfamily a member 2 (Q08379) · a predicted model of the same protein · chain B against A, TM-score 0.26
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BQQ3
- Every structure of UniProt Q08379
- Elsewhere: RCSB PDB 4REY · PDBe 4REY · UniProt Q9BQQ3 · UniProt Q08379
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