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The crystal structure of a functionally-unknown protein from legionella pneumophila subsp. pneumophila str. philadelphia 1

Analyse The crystal structure of a functionally-unknown protein from legionella… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4RD8
Type: protein
Length: 428 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein
UniProt: Q5ZU48
Pockets: 5 · best druggability 0.51

Structure

x-ray diffraction · 2 distinct chains · 63% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein	protein	210	64% helix, 2% strand	Q5ZU48
B	Uncharacterized protein	protein	218	61% helix, 2% strand	Q5ZU48

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.51	0.86	19	empty
2	69	0.46	0.83	16	empty
3	88	0.40	0.77	17	empty
4	71	0.39	0.78	17	empty
5	63	0.38	0.79	13	empty

Interfaces

1 interface between chains.

A–B · 854 Å² buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 11 modified (engineered).

Compared structures

4RD8 · The crystal structure of a functionally-unknown protein from Legionella pneumophila… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5ZU48
Elsewhere: RCSB PDB 4RD8 · PDBe 4RD8 · UniProt Q5ZU48

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