Research workbench
Crystal structure of pig dihydrolipoamide dehydrogenase
Analyse Crystal structure of pig dihydrolipoamide dehydrogenase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1IVI
- Type
- protein
- Length
- 2,390 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dihydrolipoamide dehydrogenase
- EC
- 1.8.1.4
- Pockets
- 18 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D, B, E, C | Dihydrolipoamide dehydrogenase (EC 1.8.1.4) | protein | 478 | 0% helix, 0% strand | — |
Pockets
18 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 579 | 0.64 | 0.73 | 118 | empty |
| 2 | 241 | 0.52 | 0.74 | 50 | empty |
| 3 | 253 | 0.52 | 0.73 | 59 | empty |
| 4 | 155 | 0.45 | 0.74 | 37 | empty |
| 5 | 146 | 0.44 | 0.73 | 36 | empty |
Interfaces
2 interfaces between chains.
- A–D · 466 Ų buried · 0 hydrogen bonds · protein-protein
- B–E · 466 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1IVI · Crystal Structure of pig dihydrolipoamide dehydrogenase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1IVI · PDBe 1IVI
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