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Crystal structure of human SLITRK1
Analyse Crystal structure of human SLITRK1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4RCW
- Type
- protein
- Length
- 466 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Slit and ntrk-like protein 1
- UniProt
- Q96PX8
- Pockets
- 5 · best druggability 0.83
Structure
x-ray diffraction · 2 distinct chains · 13% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Slit and ntrk-like protein 1 | protein | 234 | 13% helix, 20% strand | Q96PX8 |
| B | Slit and ntrk-like protein 1 | protein | 232 | 13% helix, 20% strand | Q96PX8 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 626 | 0.83 | 0.88 | 82 | empty |
| 2 | 785 | 0.69 | 0.76 | 77 | empty |
| 3 | 76 | 0.53 | 0.85 | 17 | empty |
| 4 | 68 | 0.41 | 0.80 | 15 | empty |
| 5 | 56 | 0.31 | 0.76 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1509 Ų buried · 20 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96PX8
- Elsewhere: RCSB PDB 4RCW · PDBe 4RCW · UniProt Q96PX8
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