Research workbench
Dengue virus serotype 3 methyltransferase without a bound S-adenosyl methionine
Analyse Dengue virus serotype 3 methyltransferase without a bound S-adenosyl methionine in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4R8R
- Type
- protein
- Length
- 512 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nonstructural protein NS5
- EC
- 2.1.1.56, 2.1.1.57
- UniProt
- C1KBQ3
- Pockets
- 4 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Nonstructural protein NS5 (EC 2.1.1.56, 2.1.1.57) | protein | 256 | 37% helix, 16% strand | C1KBQ3 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 588 | 0.67 | 0.77 | 53 | empty |
| 2 | 499 | 0.65 | 0.77 | 47 | empty |
| 3 | 61 | 0.40 | 0.81 | 18 | empty |
| 4 | 79 | 0.32 | 0.74 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 556 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 4R8R · Dengue virus serotype 3 methyltransferase without a bound S-adenosyl methionine · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C1KBQ3
- Elsewhere: RCSB PDB 4R8R · PDBe 4R8R · UniProt C1KBQ3
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