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Crystal structure of fvo strain plasmodium falciparum AMA1

Analyse Crystal structure of fvo strain plasmodium falciparum AMA1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4R1A
Type: protein
Length: 265 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Apical membrane antigen 1
UniProt: P50490
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 17% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Apical membrane antigen 1	protein	265	17% helix, 31% strand	P50490

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.35	0.78	17	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

4R1A · Crystal Structure of FVO strain Plasmodium falciparum AMA1 · the same entry in another collection · chain A against A, TM-score 1.00
P50490 · AlphaFold monomer V2.0 prediction for apical membrane antigen 1 (P50490) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P50490
Elsewhere: RCSB PDB 4R1A · PDBe 4R1A · UniProt P50490

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