Research workbench
Crystal structure of C-terminus truncated alkylhydroperoxide reductase subunit C (AHPC1-182) from E. COLI
Analyse Crystal structure of C-terminus truncated alkylhydroperoxide reductase subunit… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4QL9
- Type
- protein
- Length
- 829 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alkylhydroperoxide reductase subunit C
- UniProt
- C6EK89
- Pockets
- 14 · best druggability 0.71
Structure
x-ray diffraction · 3 distinct chains · 30% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, E | Alkylhydroperoxide reductase subunit C | protein | 165 | 32% helix, 28% strand | C6EK89 |
| B, C | Alkylhydroperoxide reductase subunit C | protein | 166 | 29% helix, 29% strand | C6EK89 |
| D | Alkylhydroperoxide reductase subunit C | protein | 167 | 29% helix, 29% strand | C6EK89 |
Pockets
14 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 127 | 0.71 | 0.91 | 21 | empty |
| 2 | 134 | 0.69 | 0.89 | 21 | empty |
| 3 | 131 | 0.52 | 0.81 | 30 | empty |
| 4 | 53 | 0.50 | 0.87 | 27 | empty |
| 5 | 62 | 0.49 | 0.86 | 26 | empty |
Interfaces
4 interfaces between chains.
- C–D · 1333 Ų buried · 16 hydrogen bonds · protein-protein
- A–B · 1225 Ų buried · 16 hydrogen bonds · protein-protein
- D–E · 672 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 672 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 4QL9 · Crystal structure of C-terminus truncated Alkylhydroperoxide Reductase subunit C… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C6EK89
- Elsewhere: RCSB PDB 4QL9 · PDBe 4QL9 · UniProt C6EK89
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.