Research workbench
Solution structure of the HMTH1, a nucleotide pool sanitization enzyme
Analyse Solution structure of the HMTH1, a nucleotide pool sanitization enzyme in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1IRY
- Type
- protein
- Length
- 156 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- HMTH1
- EC
- 3.1.6.-
- UniProt
- P36639
- Pockets
- 2 · best druggability 0.60
Structure
solution nmr · 1 distinct chain · 15% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | HMTH1 (EC 3.1.6.-) | protein | 156 | 15% helix, 40% strand | P36639 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 276 | 0.60 | 0.79 | 33 | empty |
| 2 | 75 | 0.35 | 0.76 | 15 | empty |
Compared structures
- 1IRY · Solution structure of the hMTH1, a nucleotide pool sanitization enzyme · the same entry in another collection · chain A against A, TM-score 1.00
- P36639 · AlphaFold monomer V2.0 prediction for 7,8-dihydro-8-oxoguanine triphosphatase (P36639) · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P36639
- Elsewhere: RCSB PDB 1IRY · PDBe 1IRY · UniProt P36639
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