Research workbench
Crystal structure of a macrocyclic beta-sheet peptide containing two beta-strands from amyloid beta residues 15-23
Analyse Crystal structure of a macrocyclic beta-sheet peptide containing two… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4Q8D
- Type
- protein
- Length
- 34 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Macrocyclic beta-sheet peptide incorporating residues amyloid beta 15-23
- Ligands
- HAO
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 53% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Macrocyclic beta-sheet peptide incorporating residues amyloid beta 15-23 | protein | 17 | 0% helix, 53% strand | — |
Ligands and binding sites
- HAO · {[3-(hydrazinocarbonyl)-4-methoxyphenyl]amino}(oxo) acetic acid · ligand · 2 copies · chains A, B
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 457 Ų buried · 14 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified, 4 covalent (nonstandard, covalent ligand).
Compared structures
- 4Q8D · Crystal structure of a macrocyclic beta-sheet peptide containing two beta-strands from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4Q8D · PDBe 4Q8D
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