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PIH1D1 N-terminal domain

Analyse PIH1D1 N-terminal domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4PSF
Type: protein
Length: 268 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PIH1 domain-containing protein 1
UniProt: Q9NWS0
Pockets: 4 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	PIH1 domain-containing protein 1	protein	134	28% helix, 30% strand	Q9NWS0

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	202	0.46	0.74	43	empty
2	77	0.37	0.76	13	empty
3	62	0.36	0.78	21	empty
4	106	0.35	0.73	15	empty

Interfaces

1 interface between chains.

A–B · 372 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

4PSF · PIH1D1 N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9NWS0 · AlphaFold monomer V2.0 prediction for PIH1 domain-containing protein 1 (Q9NWS0) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NWS0
Elsewhere: RCSB PDB 4PSF · PDBe 4PSF · UniProt Q9NWS0

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