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Crystal structure of an XRN1-resistant RNA from the 3' untranslated region of a flavivirus (murray valley encephalitis virus)

Analyse Crystal structure of an XRN1-resistant RNA from the 3' untranslated region of a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4PQV
Type
RNA
Length
68 nucleotides
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
XRN1-resistant flaviviral RNA
Ligands
MG
Pockets
2 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
AXRN1-resistant flaviviral RNArna68——

Ligands and binding sites

  • MG · Magnesium ion · metal · 9 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13990.560.7527MG
21630.430.7613MG

Compared structures

  • 4PQV · Crystal structure of an Xrn1-resistant RNA from the 3' untranslated region of a… · the same entry in another collection · chain A against A, TM-score 1.00

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