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Crystal structure of the mycobacterium tuberculosis tat-secreted protein RV2525C in complex with hepes (monoclinic crystal form II)

Analyse Crystal structure of the mycobacterium tuberculosis tat-secreted protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4PMR
Type: protein
Length: 202 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tat-secreted protein RV2525C
UniProt: P95028
Ligands: NA
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tat-secreted protein RV2525C	protein	202	36% helix, 21% strand	P95028

Ligands and binding sites

NA · Sodium ion · metal · chains A
EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	160	0.46	0.76	28	EPE

Compared structures

4PMR · Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P95028
Elsewhere: RCSB PDB 4PMR · PDBe 4PMR · UniProt P95028

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