Research workbench
The structure of a conserved piezo channel domain reveals a novel beta sandwich fold
Analyse The structure of a conserved piezo channel domain reveals a novel beta sandwich… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4PKX
- Type
- protein
- Length
- 235 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein C10C5.1, isoform I
- UniProt
- O01260
- Pockets
- 2 · best druggability 0.45
Structure
x-ray diffraction · 1 distinct chain · 24% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein C10C5.1, isoform I | protein | 235 | 24% helix, 34% strand | O01260 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 83 | 0.45 | 0.81 | 21 | empty |
| 2 | 104 | 0.37 | 0.75 | 21 | empty |
Compared structures
- 4PKX · The structure of a conserved Piezo channel domain reveals a novel beta sandwich fold · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O01260
- Elsewhere: RCSB PDB 4PKX · PDBe 4PKX · UniProt O01260
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