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Crystal structure of cobyrinic acid A,C-diamide synthase from mycobacterium smegmatis

Analyse Crystal structure of cobyrinic acid A,C-diamide synthase from mycobacterium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4PFS
Type: protein
Length: 491 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cobyrinic acid A,C-diamide synthase
UniProt: A0QTQ5
Pockets: 5 · best druggability 0.41

Structure

x-ray diffraction · 2 distinct chains · 44% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cobyrinic acid A,C-diamide synthase	protein	245	44% helix, 16% strand	A0QTQ5
B	Cobyrinic acid A,C-diamide synthase	protein	246	43% helix, 17% strand	A0QTQ5

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	72	0.41	0.80	23	empty
2	146	0.39	0.74	20	empty
3	74	0.37	0.77	18	empty
4	58	0.35	0.78	18	empty
5	79	0.34	0.75	21	empty

Interfaces

1 interface between chains.

A–B · 173 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

4PFS · Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0QTQ5
Elsewhere: RCSB PDB 4PFS · PDBe 4PFS · UniProt A0QTQ5

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