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Crystal structure of bacillus anthracis ribosomal protein S8 in complex with an RNA aptamer

Analyse Crystal structure of bacillus anthracis ribosomal protein S8 in complex with an… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4PDB
Type
protein + RNA
Length
167 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
30S ribosomal protein S8; Selex RNA aptamer
UniProt
W0CSD8
Pockets
2 · best druggability 0.69

Structure

x-ray diffraction · 2 distinct chains · 28% helix, 33% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A30S ribosomal protein S8protein12928% helix, 33% strandW0CSD8
ISelex RNA aptamerrna38——

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15180.690.8033empty
2670.300.7517empty

Interfaces

1 interface between chains.

  • A–I · 927 Ų buried · 23 hydrogen bonds · protein-nucleic

Compared structures

  • 4PDB · Crystal structure of bacillus anthracis ribosomal protein S8 in complex with an RNA… · the same entry in another collection · chain A against A, TM-score 1.00

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