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Fadr, fatty acid responsive transcription factor from vibrio cholerae

Analyse Fadr, fatty acid responsive transcription factor from vibrio cholerae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4P96
Type
protein
Length
556 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Fatty acid metabolism regulator protein
UniProt
G6ZTG9
Pockets
6 · best druggability 0.85

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BFatty acid metabolism regulator proteinprotein27871% helix, 2% strandG6ZTG9

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19650.850.87112empty
2690.470.8320empty
3500.450.8511empty
4660.290.7413empty
5570.280.7414empty

Interfaces

1 interface between chains.

  • A–B · 1873 Ų buried · 26 hydrogen bonds · protein-protein

Compared structures

  • 4P96 · FadR, Fatty Acid Responsive Transcription Factor from Vibrio cholerae · the same entry in another collection · chain A against A, TM-score 1.00

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