Research workbench
Crystal structure of est-Y29,A novel penicillin-binding PROTEIN/BETA- lactamase homolog from a metagenomic library
Analyse Crystal structure of est-Y29,A novel penicillin-binding PROTEIN/BETA- lactamase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4P6B
- Type
- protein
- Length
- 769 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Est-Y29
- Pockets
- 4 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 31% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Est-Y29 | protein | 386 | 31% helix, 18% strand | — |
| B | Est-Y29 | protein | 383 | 31% helix, 19% strand | — |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1151 | 0.80 | 0.81 | 101 | empty |
| 2 | 1200 | 0.77 | 0.79 | 88 | empty |
| 3 | 50 | 0.29 | 0.76 | 18 | empty |
| 4 | 68 | 0.28 | 0.73 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1039 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 4P6B · Crystal structure of Est-Y29,a novel penicillin-binding protein/beta-lactamase homolog… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4P6B · PDBe 4P6B
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