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Crystal structure of a potent anti-HIV lectin actinohivin in complex with alpha-1,2-mannotriose

Analyse Crystal structure of a potent anti-HIV lectin actinohivin in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4P6A
Type: protein
Length: 114 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Actinohivin
UniProt: Q9KWN0
Ligands: MAN

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Actinohivin	protein	114	8% helix, 39% strand	Q9KWN0

Ligands and binding sites

MAN · alpha-D-mannopyranose · sugar · 9 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

4P6A · Crystal structure of a potent anti-HIV lectin actinohivin in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Q9KWN0 · AlphaFold monomer V2.0 prediction for actinohivin (Q9KWN0) · a predicted model of the same protein · chain A against A, TM-score 0.99

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9KWN0
Elsewhere: RCSB PDB 4P6A · PDBe 4P6A · UniProt Q9KWN0

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