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Thermotoga maritima ruvb K64R mutant

Analyse Thermotoga maritima ruvb K64R mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1IN6
Type: protein
Length: 300 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Holliday junction DNA helicase ruvb
UniProt: Q56313
Ligands: ADP, CO
Pockets: 3 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Holliday junction DNA helicase ruvb	protein	300	52% helix, 12% strand	Q56313

Ligands and binding sites

ADP · Adenosine-5'-diphosphate · ligand · chains A
CO · Cobalt (II) ion · metal · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	223	0.64	0.83	34	ADP
2	79	0.45	0.81	14	empty
3	73	0.29	0.73	18	empty

Compared structures

1IN6 · Thermotoga maritima ruvb K64R mutant · the same entry in another collection · chain A against A, TM-score 1.00
Q56313 · AlphaFold monomer V2.0 prediction for holliday junction ATP-dependent DNA helicase ruvb… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q56313
Elsewhere: RCSB PDB 1IN6 · PDBe 1IN6 · UniProt Q56313

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