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Structure of the complex of a bimolecular human telomeric DNA with coptisine

Analyse Structure of the complex of a bimolecular human telomeric DNA with coptisine in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4P1D
Type
DNA
Length
24 nucleotides
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Telomeric DNA
Ligands
KPT, K

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BTelomeric DNAdna12——

Ligands and binding sites

  • KPT · 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium · ligand · chains A, B
  • K · Potassium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 551 Ų buried · 32 hydrogen bonds · nucleic-nucleic

Compared structures

  • 4P1D · Structure of the complex of a bimolecular human telomeric DNA with Coptisine · the same entry in another collection · chain A against A, TM-score 1.00

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